Applied biomedical microbiology : a biofilms approach by Daryl S. Paulson

By Daryl S. Paulson

From the slippery protecting on rocks in a circulate, to the clogging slime in a tub drain, biofilms are found in way of life in a number of varieties. This possible risk free build-up additionally bills for eighty percentage of all microbial infections. With chapters authored through skilled participants from academia and undefined, Applied Biomedical Microbiology: A Biofilms procedure demonstrates powerful how you can strive against the well-being and financial havoc that biofilms are wreaking, whereas additionally tapping into their optimistic strength.

Replete with Tables and Illustrations, Many in Color

Under the editorial tips of esteemed business microbiologist Dr. Daryl Paulson, this ebook provides an in-depth dialogue of medically hard biofilms. It offers an excellent beginning within the easy microbiology of biofilms after which is going directly to talk about the biofilms linked to clinical units, catheters, and dental unit water strains in addition to those who impression cardiovascular drugs, the gastrointestinal approach, periodontal illness, and persistent wounds. This informative paintings concludes with an exploratory bankruptcy of a few of the equipment used to enquire biofilms.

Applied Biomedical Microbiology: A Biofilms process presents key details basically and concisely – an invaluable advisor for environmental, nutrition, and water microbiologists in addition to biochemists, pharmaceutical scientists, and product and biofilm engineers.

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Mechanisms of bacterial-mediated resistance in oral biofilms Some bacteria are intrinsically resistant to various antibiotics. For example, aerobic bacteria are generally resistant to metronidazole. Other bacteria may lack the target site of the antibiotic, or lack the transport mechanisms needed to import the drug from the extracellular environment. However, treatment of intrinsically resistant bacteria can usually be achieved with an alternative drug. Acquired antibiotic resistance, however, is more problematic.

Natl. Acad. Sci. USA 88, 4781, 1991. 23. , et al. Novel tetracycline resistance determinant from the oral metagenome. Antimicrob. Agents Chemother. 47, 1430, 2003. 24. A. Bacterial resistance to tetracycline: Mechanisms, transfer and clinical significance. Clin. Microbiol. Rev. 5, 387, 1992. 25. , et al. The maintenance in the oral cavity of children of tetracycline resistant bacteria and the genes encoding such resistance. J. Antimicrob. Chemother. 56, 524, 2005. 26. , et al. Prevalence and identification of tetracycline-resistant oral bacteria in children not receiving antibiotic therapy.

The mobile DNA is shown as thick gray lines, and chromosomal DNA is shown as thin lines. Cell membranes are thin black lines. A: Transformation—A bacterial cell has lysed and the DNA has been released, where it transforms a competent cell. B: Transduction—a phage particle infects a bacterial cell with its genome, which also contains a region of DNA from the previous bacterial host (thick gray line). C1: Conjugation of a conjugative plasmid from one cell to another; can occur through a pilus. C2: Conjugation of a conjugative transposon, requiring intimate cell-to-cell contact.

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